As a physical scientist, I would say usually not. As a geologist, though, you have to be really careful when making observations to try and record what is actually there – as there is a strong tendency otherwise to only record the things you ‘expect’ to see, based on your feelings about what you think is going on!
An experiments outcomes depends on the inputs, you must do something differently to affect it so simply teh way you are feeling shouldn’t make any difference to the findings.
That’s why it is very important to plan the experiment carefully in order to minimise those risks. For instance, if I expect a drug to have a certain effect on cells, I might (unconsciously) look for that effect more thoroughly in cells that have been treated than in untreated cells. So I might pick it up in treated cells, but not in untreated cells. One way to go about this would be to have somebody else label my samples such that when I am looking at them, I don’t know which cells are treated and which ones are untreated. Or I could let somebody else check the cells under the microscope without telling them what it is I’m looking for. Or I might take pictures of the cells and let a computer analyse the images in order to rule out human bias.
Yes, definitely!! I will respond to your question differently depending on my mood 😉
People will respond differently if you ran an experiment on different days. This is why scientists are willing to accept a degree of chance in their data. So, when I find that one group in my experiment outperforms another group, I will only state that they are different when the difference is beyond a 95% probability of it happening outside of chance occurrences (like someone just happens to be in a bad mood). Also, many of my experiments have more than 100 people participating, so that summarizing across all the people, you can manage chance occurrences.
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